2022 Lexus RX 350 Problems & Owner Complaints

Unknown Or Other 10 1 crash 1 fire

“Driving on I80E in Iowa with cruise control set at 70 mph, warning light for AWD failure came on, followed by engine light and all warning lights. Coasted into breakdown lane and had definite loss of power. Became aware of fire by fellow motorist running toward the car with fire extinguisher. Saw black smoke and fire coming from front of car. Forced to evacuate car on interstate, smoke in east and westbound lanes. The car was consumed in about 20 minutes. Insurance company- AAA - has inspected car. Unknown if Lexus has inspected. Remains taken to Teo’s Towing 563-888-1988. Please inspect. Air…”
NHTSA complaint #11464628, 2022 · fire

“On July 15, 2022, my 2022 RX450hL drove itself across approximately 150 feet of rugged desert terrain and ended upside down in my neighbor's driveway. No one was in the car and no one was in the driveway where it landed. I had parked the car on the side of my house, after several seconds the car took off across the desert to self-destruct. I contacted Lexus, someone from their legal dept. contacted me and they sent a representative to collect the "black box." After that Lexus refused to take my calls or provide any information to me about the "black box." I had taken possession of the…”
NHTSA complaint #11540444, 2022 · crash

“I purchased the 2022 Lexus RX 350 used a couple of months ago. While driving down the highway the instrument panel went blank. I was terrified. I continued to drive not knowing what speed I was driving. The instrument panel went panel came back minutes later. Another incident occurred when the car was parked in my driveway. I turned on the engine and the instrument panel was blank. No numbers and no information on the instrument panel. As I drove down the street slowly the instrument panel returned to normal. A third incident occurred when occurred as we were driving on the highway. The…”
NHTSA complaint #11714267, 2025

Electrical System 6 1 crash

“HI, I purchased a brand new 2022 Lexus RX350 from Hendrick Lexus of Charleston SC. Since day one I had dangerous issues below: 1. The transmission shifts up and down so hard, I've almost gotten rear ended due to the car and not braking. This I was told by two separate Lexus dealers I'm feeling a hard "transmission gap"-whatever that means. To add fuel to this dangerous defect is my autistic son would need to be specially medicated to ride in the car b/c he panics and tries to jump out. 2. The car also is equipped with a "rear kick sensor" that never worked, The service manager in Charlest…”
NHTSA complaint #11689819, 2022 · crash

“I purchased the 2022 Lexus RX 350 used a couple of months ago. While driving down the highway the instrument panel went blank. I was terrified. I continued to drive not knowing what speed I was driving. The instrument panel went panel came back minutes later. Another incident occurred when the car was parked in my driveway. I turned on the engine and the instrument panel was blank. No numbers and no information on the instrument panel. As I drove down the street slowly the instrument panel returned to normal. A third incident occurred when occurred as we were driving on the highway. The…”
NHTSA complaint #11714267, 2025

“Wireless charger caused iPhone 12 to overheat. Picked phone up from charger before it became to hot to handle. Dealership admits issue, "there has been a significant improvement in wireless charging in our cars over the past couple of years. The wireless charging on our earlier models do have connectivity issues and sometimes may even overheat, especially in iPhone. This is a known issue with no resolution currently, unfortunately. I hope this helps." If the dealership recognizes an issue with overheating, I suggest a recall before the charger or phone starts a fire.”
NHTSA complaint #11685145, 2024

Fuel/Propulsion System 5 2 crash 1 fire 2 injury

“The accident happened when I was using the "BRAKE HOLD SYSTEM". It is designed to use when the needs to stop briefly. When the Brake Hold button is touched while the driver's foot is on the brake pedal, the driver do not need to step on the brake even though the shift lever is in D. After I finished paying for a car wash, I touched the Brake Hold button. Then the vehicle suddenly accelerated forward and ran at a high speed. I was pushing the brake pedal, when I touched the button. I was startled and attempted to stop the vehicle with all my strength by braking the brake pedal. It didn't stop a…”
NHTSA complaint #11623542, 2024 · crash · fire · 2 injury(ies)

“My wife was driving the subject car She intended to come off the road to give a way to on coming car. She got in naghbour's drive way and intended move 10 feet. When she tried to put more gas to move the car was hyper accepting drove 50 feets away and hit naghbour's ion gate and stopped. When she back off it did again and hit street lamp. It did two more time. Ended up damaging 4 corners of the car and all the material that the car hit. I could not understand that she hit the 4 corner of the car. That is why I suspected engine problem. When I tried the same movement nàghbour came out and worry…”
NHTSA complaint #11748336, 2026 · crash

“I have a 2022 Lexus RX350 F Sport. There are many complaints for this problem with this era of Lexus that happen daily. When pulling out into traffic the vehicle stutters or hesitates; this could cause a serious accident with injuries or death. I think it is a problem with the transmission shift programming. In an attempt to be fuel efficient, Lexus created a serious safety problem in my opinion. My car is under warranty, I brought it to the dealer and they said that is normal and a known issue with that era of Lexus; there is no fix or repair. Despite being under warranty, I pai…”
NHTSA complaint #11699530, 2025

Service Brakes 5 1 crash 1 fire 2 injury

“The accident happened when I was using the "BRAKE HOLD SYSTEM". It is designed to use when the needs to stop briefly. When the Brake Hold button is touched while the driver's foot is on the brake pedal, the driver do not need to step on the brake even though the shift lever is in D. After I finished paying for a car wash, I touched the Brake Hold button. Then the vehicle suddenly accelerated forward and ran at a high speed. I was pushing the brake pedal, when I touched the button. I was startled and attempted to stop the vehicle with all my strength by braking the brake pedal. It didn't stop a…”
NHTSA complaint #11623542, 2024 · crash · fire · 2 injury(ies)

“The contact owns a 2022 Lexus RX450H. The contact stated while driving 35 MPH on a rainy day, the brake pedal was depressed; however, there was an abnormal squishing sound coming from the brake pedal, and the vehicle failed to stop as intended. The contact stated the vehicle went through the stop light and up onto a curb before the vehicle stopped. The vehicle was not diagnosed or repaired by an independent mechanic or the dealer. Additionally, the contact stated that the failure had occurred previously. The vehicle was taken to the dealer; however, the dealer confirmed the abnormal squishing…”
NHTSA complaint #11644807, 2025

“I am writing to formally express my serious concerns regarding the brake actuator on my Lexus vehicle, which remains unrepaired despite being under warranty. This issue poses a significant danger to both myself and the public, and I am seeking an urgent resolution. I have been a proud owner of my Lexus RX450H 2022, and the vehicle is currently under warranty. Recently, I visited the Lexus dealership in Roseville, California, where it was recommended that the brake actuator be repaired due to its faulty condition. Despite this recommendation and the warranty coverage, the repair has not been c…”
NHTSA complaint #11628066, 2024

Engine 4 1 crash

“My wife was driving the subject car She intended to come off the road to give a way to on coming car. She got in naghbour's drive way and intended move 10 feet. When she tried to put more gas to move the car was hyper accepting drove 50 feets away and hit naghbour's ion gate and stopped. When she back off it did again and hit street lamp. It did two more time. Ended up damaging 4 corners of the car and all the material that the car hit. I could not understand that she hit the 4 corner of the car. That is why I suspected engine problem. When I tried the same movement nàghbour came out and worry…”
NHTSA complaint #11748336, 2026 · crash

“I have a 2022 Lexus RX350 F Sport. There are many complaints for this problem with this era of Lexus that happen daily. When pulling out into traffic the vehicle stutters or hesitates; this could cause a serious accident with injuries or death. I think it is a problem with the transmission shift programming. In an attempt to be fuel efficient, Lexus created a serious safety problem in my opinion. My car is under warranty, I brought it to the dealer and they said that is normal and a known issue with that era of Lexus; there is no fix or repair. Despite being under warranty, I pai…”
NHTSA complaint #11699530, 2025

“Severe droning vibrations coming from the exhaust when driving at 1500rpm @ 30mph and 60mph. Can be easily repeated at the aforementioned speeds. Problem has been identified by dealer, but dealer does not have a fix for 2022 RX350 model. Problem appeared while taking the suv home after delivery.”
NHTSA complaint #11551738, 2022

Tires 4

“We bought the brand new Lexus (RX450H) back in 2022 (Vin [XXX] ). As of today, February 03, 2025, the mileage on the car is 20,125 miles. The OEM tire size was 235/55R20, all the 4 tires were Bridgestone Ecopia H/L [XXX] . Recently, one of the wheels exploded when it passed a pothole, the tire was damaged and the rim was bent/cracked as well. I brought one tire, same brand and size, and installed it to the new Lexus rim. The installer told me that these tires were "Recalled" and suggested to replace all 4 tires ASAP. I Google and found these recalled tires as well. As of now, couple other t…”
NHTSA complaint #11640530, 2024

“Driving on freeway, sudden blowout causing loss of braking ability. Barely managed to pull to shoulder sidewall completely shredded.”
NHTSA complaint #11618201, 2024

Power Train 3 1 crash

“HI, I purchased a brand new 2022 Lexus RX350 from Hendrick Lexus of Charleston SC. Since day one I had dangerous issues below: 1. The transmission shifts up and down so hard, I've almost gotten rear ended due to the car and not braking. This I was told by two separate Lexus dealers I'm feeling a hard "transmission gap"-whatever that means. To add fuel to this dangerous defect is my autistic son would need to be specially medicated to ride in the car b/c he panics and tries to jump out. 2. The car also is equipped with a "rear kick sensor" that never worked, The service manager in Charlest…”
NHTSA complaint #11689819, 2022 · crash

“The vehicle hesitates with apparent gear dragging and audible whining or grinding noises. The condition worsens when driving uphill and includes occasional sudden increases to high RPMs during normal acceleration. A slight burning odor is sometimes present after driving, along with lower-than-expected fuel economy in city and highway driving. The transmission exhibits harsh shifting, hesitation, and loss of smooth acceleration, negatively affecting drivability and raising safety concerns. Dealer inspections have not resolved the issue and claim the condition is normal.”
NHTSA complaint #11711476, 2026

“I have a 2022 Lexus RX350 F Sport. There are many complaints for this problem with this era of Lexus that happen daily. When pulling out into traffic the vehicle stutters or hesitates; this could cause a serious accident with injuries or death. I think it is a problem with the transmission shift programming. In an attempt to be fuel efficient, Lexus created a serious safety problem in my opinion. My car is under warranty, I brought it to the dealer and they said that is normal and a known issue with that era of Lexus; there is no fix or repair. Despite being under warranty, I pai…”
NHTSA complaint #11699530, 2025

Air Bags 2 2 crash 2 injury

“Making a left turn at night going about 10 mph I was struck by a car with no lights. He hit the right front of my vehicle going about 55-60 mph. He hit my front strut and headlights and grill and radiator. My airbags did not deploy, the other vehicle’s airbag did. The police told me I should call Lexus and report the problem. The insurance company totaled my vehicle..”
NHTSA complaint #11707416, 2025 · crash · 1 injury(ies)

“I was a passenger in an accident. I was sitting in the front passenger seat. We were sitting in standstill traffic. Our vehicle was struck from behind; it caused the vehicle to shift and was hit again on front driver side of the vehicle. Airbag’s deployed on the driver side (front and back) but not the front passenger. Seatbelts were worn. I suffered a concussion and a herniated disc.”
NHTSA complaint #11483867, 2022 · crash · 1 injury(ies)

Back Over Prevention 2 1 crash

“HI, I purchased a brand new 2022 Lexus RX350 from Hendrick Lexus of Charleston SC. Since day one I had dangerous issues below: 1. The transmission shifts up and down so hard, I've almost gotten rear ended due to the car and not braking. This I was told by two separate Lexus dealers I'm feeling a hard "transmission gap"-whatever that means. To add fuel to this dangerous defect is my autistic son would need to be specially medicated to ride in the car b/c he panics and tries to jump out. 2. The car also is equipped with a "rear kick sensor" that never worked, The service manager in Charlest…”
NHTSA complaint #11689819, 2022 · crash

“Car turned on and no driving yet. All vehicle alert signs popped up. This is brand new car. Warning signs including: Anti-lock brak system advanced ultrasonic detection parking braking system pre-collision system blind spot monitor These signs are constantly popping up without any hazard condition. Lexus keeps refusing to do thorough exam because they keep stating there is no issues with the vehicle.”
NHTSA complaint #11543228, 2023

Exterior Lighting 2

“I purchased the 2022 Lexus RX 350 used a couple of months ago. While driving down the highway the instrument panel went blank. I was terrified. I continued to drive not knowing what speed I was driving. The instrument panel went panel came back minutes later. Another incident occurred when the car was parked in my driveway. I turned on the engine and the instrument panel was blank. No numbers and no information on the instrument panel. As I drove down the street slowly the instrument panel returned to normal. A third incident occurred when occurred as we were driving on the highway. The…”
NHTSA complaint #11714267, 2025

“I have already contacted the dealer and Lexus corporate. If you drive this car with polarized sunglasses all of your gauges disappear and you have no idea of anything with respect to the automobile such as speed or any of the other indications. I was told that they agree that this is a design defect but they will not do anything about it and if they do do something in the future then I should keep watching for a recall. I told them that being unable to wear sunglasses when you have sensitive eyes is unacceptable and not being able to see a single gauge including the heads up display is absolut…”
NHTSA complaint #11490564, 2022

Visibility/Wiper 2

“My 2022 RX , the driver side outer rear view mirror image vibration while driving on highway at speed around 60 mph +/- then start shaking. Report the issue to dealer when regular service, the mechanic report this is normal after inspect the problem, but this vibration and shaking is really annoying while driving on highway. Some drivers may have the same issue and cause some risks.”
NHTSA complaint #11491084, 2022

“Mirror of driver side vibration when driving. This cause of double image effected driving safety.”
NHTSA complaint #11466526, 2022

Carry Handle 1

“The seatbelt install will not stay tight, the seatbelt slips easily out of the lockoff. This happens in all seating positions in this vehicle but does not happen in our other vehicles.”
NHTSA complaint #11629503, 2023

Forward Collision Avoidance 1 1 crash

“On July 15, 2022, my 2022 RX450hL drove itself across approximately 150 feet of rugged desert terrain and ended upside down in my neighbor's driveway. No one was in the car and no one was in the driveway where it landed. I had parked the car on the side of my house, after several seconds the car took off across the desert to self-destruct. I contacted Lexus, someone from their legal dept. contacted me and they sent a representative to collect the "black box." After that Lexus refused to take my calls or provide any information to me about the "black box." I had taken possession of the…”
NHTSA complaint #11540444, 2022 · crash

Fuel System 1

“The contact owns a 2022 Lexus RX 350. The contact stated that after refueling, there was an abnormally strong fuel odor coming from the vehicle. The odor was more pronounced while the vehicle was parked in the garage, and the garage was filled with a gasoline odor. There were no warning lights illuminated. The vehicle was taken to the dealer, who diagnosed the vehicle with a failure of the high-pressure fuel pump. The high-pressure fuel pump was replaced; however, the failure persisted. The vehicle was returned to the dealer approximately 3 weeks later. The contact stated that the battery and…”
NHTSA complaint #11700076, 2025

Lane Departure 1

“Car turned on and no driving yet. All vehicle alert signs popped up. This is brand new car. Warning signs including: Anti-lock brak system advanced ultrasonic detection parking braking system pre-collision system blind spot monitor These signs are constantly popping up without any hazard condition. Lexus keeps refusing to do thorough exam because they keep stating there is no issues with the vehicle.”
NHTSA complaint #11543228, 2023

Vehicle Speed Control 1 1 crash 1 fire 2 injury

“The accident happened when I was using the "BRAKE HOLD SYSTEM". It is designed to use when the needs to stop briefly. When the Brake Hold button is touched while the driver's foot is on the brake pedal, the driver do not need to step on the brake even though the shift lever is in D. After I finished paying for a car wash, I touched the Brake Hold button. Then the vehicle suddenly accelerated forward and ran at a high speed. I was pushing the brake pedal, when I touched the button. I was startled and attempted to stop the vehicle with all my strength by braking the brake pedal. It didn't stop a…”
NHTSA complaint #11623542, 2024 · crash · fire · 2 injury(ies)